DP13 A case of poikilodermatous plaque-like haemangioma: a newly described entity

Abstract A 56-year-old man was referred with a 1.5 cm × asymptomatic erythematous and scaly plaque on his right upper calf of 6 months’ duration. He had no similar lesions or prior skin issues. significant comorbidities regular medications. There known family history relevance. The initial clinical findings were felt to be in keeping Bowen disease. treated once cryotherapy, followed by two cycles 5-fluorouracil cream, applied daily over 4 weeks. Despite this, the persisted increased size, measuring 3 2.5 cm. 4-mm incisional biopsy performed. Histopathology showed an acanthotic epidermis compact hyperkeratosis, overlying superficial dermal vascular lesion that consisted distinctive band-like proliferation small endothelial cell-lined vessels. Background fibrosis oedema noted, as well loss elastic fibres within lesional area, demonstrated van Gieson stain. Positive immunohistochemistry staining included CD31 erythroblast transformation-specific-related gene stains, helping confirm this lesion’s origin, negative result for D2-40 (podoplanin), suggesting lymphatic involvement. histological appearances thought fit diagnosis poikilodermatous plaque-like haemangioma (PPLH), newly described entity acquired proliferation. Poikilodermatous haemangioma, first 2019, usually presents solitary atrophic erythematous-to-violaceous typically found lower limbs (Semkova K, Carr R, Grainger M et al. hemangioma: case series defined entity. J Am Acad Dermatol 2019; 81:1257–70). Reassuringly, it has benign course, but can persistent al.). Our patient keen treatment continuing grow, causing him concern. However, there is sparse information available literature regarding effective treatments PPLH. discussed at departmental clinicopathological meeting. too merit any radiological investigation soft tissues. Surgical excision given size location would most likely require large graft. Sclerotherapy considered not appropriate setting. trial laser therapy regarded best option nature lesion. since started course pulsed dye (PDL) wavelength 585 nm, we wait interest determine if effective. We therefore present raise awareness PPLH consider differential sun-protected site.